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January 8, 2015
TUSTIN, Calif., Jan. 8, 2015 – Non-contrast enhanced MR angiography (MRA) techniques have attracted interest in the medical community for diagnosing renal artery stenosis, as it eliminates the need for gadolinium-based contrast agents used with CT angiography (CTA). In an international multi-center trial REACT (REnal Artery Contrast-free Trial), Toshiba’s Time-Spatial Labeling Inversion Pulse (Time-SLIP) is validated as a robust technique for non-contrast vascular imaging while providing an accurate and non-invasive method for diagnosing patients.
The results from the multi-center trial demonstrated the high sensitivity, specificity and diagnostic accuracy of Time-SLIP while also showing no statistical differences between non-contrast MRA and CTA in terms of their ability to visualize renal artery stenosis. The results from the trial were published in the January 2015 issue of American Journal of Roentgenology.
“Toshiba’s corporate philosophy is ‘Made for Life™,’ and it is one of our missions to minimize patients’ risk while providing exceptional images for their best possible medical treatment,” said Toshio Takiguchi, president, Toshiba Medical Systems Corporation (TMSC). “The REACT study has proved that it is now possible to detect renal artery stenosis without using contrast agents. Time-SLIP eliminates the need for gadolinium-based contrast agents, which results in safer and more comfortable examinations. Not only do these non-invasive and painless techniques eliminate the risks associated with gadolinium-based contrast agents, but they also require less setup time for clinicians, resulting in MR exams that are more comfortable for the patient and can be completed more quickly without compromising image quality.”
The trial consisted of 75 patients in collaboration with seven medical centers in five countries: the United States, Spain, China, France and Japan. All subjects underwent medically required non-contrast renal MRA exams, using the 1.5T Vantage AtlasTM and Vantage TitanTM MR systems, as well as CT angiography for the evaluation of renal artery stenosis.
“This is a first-of-its-kind multi-center, international, non-contrast vascular imaging trial,” said Dr. Timothy Albert, director, Cardiovascular Diagnostic Center at Salinas Valley Memorial Healthcare System, who served as the principal investigator of the trial. “It exemplifies the long-term commitment that Toshiba has to not only developing novel imaging solutions but providing clinical evidence to support them. REACT shows that Time-SLIP imaging can be user-friendly and applied to different patient groups. It works in diverse populations, from Asia to Europe and the United States.”
About Toshiba America Medical Systems, Inc.
With headquarters in Tustin, Calif., Toshiba America Medical Systems (TAMS) markets, sells, distributes and services radiology and cardiovascular systems, including CT, MR, ultrasound, X-ray and cardiovascular equipment, and coordinates clinical diagnostic imaging research for all modalities in the United States. For more information, visit the TAMS website at www.medical.toshiba.com.
About Toshiba Medical Systems Corporation
Toshiba Medical Systems Corporation is a leading worldwide provider of medical diagnostic imaging systems and comprehensive medical solutions, such as CT, X-ray and vascular, ultrasound, nuclear medicine and MRI systems, as well as information systems for medical institutions. Toshiba Medical Systems Corporation has been providing medical products for over 80 years. Toshiba Medical Systems Corporation is a wholly owned subsidiary of Toshiba. Visit Toshiba Medical Systems Corporation’s website at www.toshibamedicalsystems.com.
Toshiba Corporation, a Fortune 500 company, channels world-class capabilities in advanced electronic and electrical products and systems into five strategic business domains: Energy & Infrastructure, Community Solutions, Healthcare Systems & Services, Electronic Devices & Components, and Lifestyles Products & Services. Guided by the principles of The Basic Commitment of the Toshiba Group, “Committed to People, Committed to the Future,” Toshiba promotes global operations towards securing “Growth Through Creativity and Innovation” and is contributing to the achievement of a world in which people everywhere live in a safe, secure and comfortable society.
Founded in Tokyo in 1875, today’s Toshiba is at the heart of a global network of over 590 consolidated companies employing over 200,000 people worldwide, with annual sales surpassing 6.5 trillion yen (US$63 billion). To find out more about Toshiba, visit www.toshiba.co.jp/index.htm.