T1-SSPH07 | MAXIMIZING IMAGE QUALITY THROUGH THE SYNERGY OF HIGH-RESOLUTION PHOTON-COUNTING DETECTOR CT AND DEEP LEARNING RECONSTRUCTION: A CORONARY PHANTOM STUDY

Toru Higaki, PhD - Hiroshima University

Conclusions: The HR PCD-CT demonstrated superior spatial resolution, beneficial for visualizing fine anatomical structures such as coronary arteries. However, this comes at the cost of increased image noise. The DLR enabled efficient noise reduction without introducing image blurring typically associated with reconstruction kernels, thereby maximizing the potential of HR PCD-CT imaging.

Clinical Relevance: The combination of HR PCD-CT and DLR has the potential to provide both high diagnostic performance and radiation dose reduction in the evaluation of coronary artery disease.

Scientific Session Tuesday, December 2, 2025 at 8:00 AM CST

T6-SSCH06-5 | QUANTITATIVE ANALYSIS OF PULMONARY EMPHYSEMA USING ELECTRON DENSITY IMAGES FROM PHOTON-COUNTING DETECTOR CT: CORRELATION WITH PULMONARY FUNCTION TESTS

Tomoaki Sasaki, MD - National Cancer Center Hospital East

Conclusions: Quantitative analysis of pulmonary emphysema using electron density images from photon-counting detector CT provides stronger correlation with pulmonary function tests compared to conventional CT density-based assessment, potentially improving the accuracy of emphysema quantification.

Clinical Relevance/Application: Electron density images from photon-counting detector CT offer improved quantitative assessment of pulmonary emphysema that correlates better with clinical pulmonary function, potentially enhancing the role of CT in monitoring disease progression and treatment response in patients with chronic obstructive pulmonary disease.

Scientific Session Tuesday, December 2, 2025 at 1:30 AM CST

S1-SSPH01-6 | PHOTON-COUNTING CT AND DEEP LEARNING RECONSTRUCTION IN LUNG LESION ASSESSMENT

Kai Mei, PhD - UPENN

Conclusions: This study demonstrates that SHR PCCT, particularly when combined with DLR, enables robust visualization and characterization of lung lesions across varying sizes, spiculation levels, and dose.

Clinical Relevance/Application: These findings highlight the clinical potential of PCCT with DLR to improve lung lesion assessment while maintaining image quality across reduced dose levels, supporting safer and more accurate low-dose CT protocols.

Scientific Session Sunday, November 30, 2025 at 9:00 AM CST

M3-SSPH04-6 | TASK-SPECIFIC EVALUATION OF PHOTON-COUNTING CT USING A 3D-PRINTED ANTHROPOMORPHIC LUNG PHANTOM WITH COPD PATHOLOGY

Fong Chi Ho, PhD - UPENN

Conclusions: This study introduces the first XCAT-based anthropomorphic lung phantom specifically designed to model COPD, featuring controlled pathological characteristics for evaluating CT technologies. While PCCT offers superior resolution in its standard NR mode, SHR mode offers further advantage in quantifying clinically relevant biomarkers for pulmonary disease.

Clinical Relevance/Application: Task-specific phantoms enable objective comparison of CT technologies for disease-specific imaging. SHR mode demonstrated a major advantage over NR mode in quantifying COPD biomarkers, emphasizing its clinical significance in thoracic imaging and management.

Scientific Session Monday, December 1, 2025 at 9:30 AM CST

W7-SSPH11-5 | ASSOCIATION BETWEEN DETECTABILITY INDEX AND VOLUMETRIC ACCURACY IN LOW-DOSE ENERGY-INTEGRATING AND PHOTON-COUNTING CT

Elsa Pimenta PhD, Gisell Ruiz Boiset, PhD - Nijmegen Radboudumc

Conclusions: d′ is inversely related to volumetric measurement error (MRE% and IQR%). Protocols utilizing DLR with LUNG kernel, particularly with PCCT, achieved the highest detectability and the lowest error.

Clinical Relevance/Application: These findings highlight the utility of d’ in protocol optimization to enhance diagnostic performance in low-dose CT imaging.

Scientific Session Wednesday, December 3, 2025 at 3:00 PM CST

T2-SPCH-12 | IMPACT OF PHOTON-COUNTING DETECTOR CT ON VISUALIZATION OF THE ADAMKIEWICZ ARTERY USING SUPER-HIGH-RESOLUTION MODE WITH DEEP LEARNING RECONSTRUCTION: A FIRST EXPERIENCE

Fuminari Tatsugami, MD – Hiroshima University

Conclusions: The SHR mode reconstructed with DLR on a PCD-CT scanner significantly improves the image quality of the AKA compared to other reconstruction methods.

Clinical Relevance/Application: The SHR mode reconstructed with DLR on a PCD-CT scanner enhances the image quality of the AKA, which may improve diagnostic performance in detecting the AKA and contribute to avoiding disruption of the AKA during aortic surgery.

Poster Discussion Tuesday, December 2, 2025 at 9:00 AM CST

W2-SPPH-7 | ASSESSING THE UTILITY OF PHOTON-COUNTING CT IN OBESE PATIENTS

Leening Liu, PhD - UPENN

Conclusions: PCCT yielded enhanced dose efficiency with lower noise compared to EID-CT at a fixed dose, enabling an average dose reduction of 36% across varying phantom sizes. This improvement is particularly impactful at larger phantom sizes and lower doses, enabling effective imaging of obese patients without compromising the image quality necessary for precise disease diagnosis and monitoring.

Clinical Relevance/Application: This dose efficiency has important clinical implications, enabling lower dose imaging protocols for obese patients without compromising diagnostic accuracy.

Poster Discussion Wednesday, December 3, 2025 at 9:00 AM CST

T5B-SPGI-7 | USE OF DARK ATTENUATION ORAL CONTRAST AGENT IMPROVES DELINEATION OF THIN STRUCTURES AT ULTRA-HIGH RESOLUTION AND PHOTON-COUNTING DETECTOR CT

Yuxin Sun BS, MS and Benjamin Yeh, MD - University of California San Francisco

Conclusions: DBCM -160 HU demonstrated the best performance for delineation of bowel fold detail compared to air, neutral, or positive oral agents, regardless of scan resolution, matrix size, or kernel, with further significant improvements seen when used in conjunction with PCD-CT compared to EID-CT.

Clinical Relevance/Application: Oral contrast profoundly affects visualization of thin structures such as bowel folds at abdominal CT, with moderately dark agents outperforming other agents, warranting clinical testing.

Poster Discussion Tuesday, December 2, 2025 at 12:45 PM CST

R5A-SPPH-4 | EVALUATION OF RECONSTRUCTION KERNELS AND RESOLUTION TECHNIQUES FOR VOLUMETRIC ACCURACY OF GROUND-GLASS OPACITY NODULES IN LOW-DOSE PHOTON-COUNTING CT

Elsa Pimenta PhD., Gisell Ruiz Boiset, PhD - Nijmegen Radboudumc

Conclusions: FC51/HR protocol exhibited consistent superior volumetric accuracy across all dose levels, particularly under low-dose conditions where precise measurements are most challenging. The differences among all protocols became less pronounced at higher dose levels. This finding underscores the benefits of high-resolution reconstruction in preserving measurement precision while minimizing radiation exposure.

Clinical Relevance/Application: This study underscores the clinical significance of selecting suitable reconstruction protocols for precise volumetric evaluation of GGO-type nodules at low-dose CT.

Poster Discussion Thursday, December 4, 2025 at 12:15 PM CST

S4-SSVA01-6 | VALUE OF CONTRAST ENHANCEMENT BOOST TECHNIQUE AT SUBMILLISIEVERT CT ANGIOGRAPHY OF THE LOWER EXTREMITIES: EFFECT ON IMAGE QUALITY AND DIAGNOSTIC ACCURACY

Meng Wang– Hanzhong Central Hospital

Conclusions: CE-boost technology significantly improves both objective and subjective image quality in optimized, submillisievert lower extremity CTA while preserving diagnostic accuracy.

Clinical Relevance/Application: CE-boost can significantly improve image quality in submillisievert lower extremity CTA without requiring any additional scanning settings or modifications to the clinical workflow.

R6-SSCA11-4 | DEEP LEARNING-DRIVEN VIRTUAL CORONARY CT ANGIOGRAPHY FOR QUANTITATIVE STENOSIS EVALUATION

Weifeng Guo– Zhongshan Hospital Affiliated to Fudan University

Conclusions: A pix2pix GAN effectively synthesized virtual CCTA from NCCT, demonstrating high concordance with real CCTA for stenosis quantification.

Clinical Relevance/Application: Virtual CCTA offers a potential alternative to contrast-enhanced CCTA, reducing iodinated contrast media use and mitigating stenosis overestimation from calcified plaque blooming artifacts.

Scientific Session Thursday, December 4, 2025 at 1:30 PM CST

W1-SSVA03-6 | BLACK-BLOOD CT COMBINED WITH CE-BOOST SIGNIFICANTLY ACCELERATES PORTAL VEIN SEGMENTATION AND ENHANCES IMAGE QUALITY

Huasong Cai – The First Affiliated Hospital of Sun Yat-sen University

Conclusions: BBCT integration with CE-boost CTA nearly halves manual portal vein segmentation time while narrowing variability and delivers superior subjective and objective image quality by effectively suppressing residual arterial signals.

Clinical Relevance/Application: Automated arterial subtraction via BBCT streamlines 3D portal vein visualization and segmentation, offering radiologists a rapid, reliable workflow for preoperative planning and diagnostic evaluation of portal venous pathology.

Scientific Session Wednesday, December 3, 2025 at 8:00 AM CST

S3A-SPVA-3 | AREA-DETECTOR CT FOR ABDOMINAL AORTIC ANEURYSM FOLLOW-UP: INFLUENCE OF GRAVITY ON IMAGE QUALITY AND DIAMETER MEASUREMENTS IN ROUTINE CLINICAL PRACTICE

Masahiko Nomura, MD, PhD – Fujita Health University

Conclusions: When AAA patients followed, upright ADCT demonstrates significantly larger diameter than supine ADCT due to gravity, although the difference had little influence on AAA management in routine clinical practice.

Clinical Relevance/Application: When AAA patients followed, upright ADCT demonstrates significantly larger diameter than supine ADCT due to gravity, although the difference had little influence on AAA management in routine clinical practice.

Poster Discussion Sunday, November 30, 2025 at 11:45 AM CST

S3A-SPVA-3 | The Value of the Contrast Enhancement Boost Technique for Renal Artery Visualization in Dynamic Contrast-Enhanced Renal CT

Dr. Ebisu, MD – Kobe University

Conclusions: The 2-step CE-boost method (CMP-[NP-CMP]) can improve the delineation of the renal artery by selectively increasing the contrast enhancement of the renal artery without increasing the renal parenchymal enhancement.

Clinical Relevance/Application: The 2-step CE-boost technique may aid preoperative vascular assessment by enabling clearer delineation of the renal arteries.

Poster Discussion Tuesday, December 2, 2025 at 9:00 AM CST

S3A-SPCA-14 | SUPER-RESOLUTION DEEP LEARNING RECONSTRUCTION FOR CORONARY CT ANGIOGRAPHY: IMPROVED CORONARY STENOSIS ASSESSMENT AND CAD-RADS RECLASSIFICATION

Limiao Zou – PUMC

Conclusions: SR-DLR outperformed HIR for coronary stenosis assessment and led to 20% patient-level CAD-RADS reclassification.

Clinical Relevance/Application: SR-DLR holds great promise in enhancing the role of CCTA in the diagnosis and patient management of coronary artery disease.

Poster Discussion Sunday, November 30, 2025 at 11:45 AM CST

M5B-SPCA-14 | IMPACT OF SUPER-RESOLUTION DEEP LEARNING RECONSTRUCTION ON CORONARY CT ANGIOGRAPHY-DERIVED PLAQUE QUANTIFICATION

Limiao Zou – PUMC

Conclusions: Compared with HIR, higher total plaque volumes were obtained with SR-DLR, with lower calcified plaque volume and higher LAP and fibrous plaque volume.

Clinical Relevance/Application: CCTA-derived plaque quanfication via SR-DLR may potentially improve risk stratification of coronary artery disease.

Poster Discussion Monday, December 1, 2025 at 12:45 PM CST

S3B-SPCA-14 | IMPROVEMENT OF CORONARY ARTERY STENT EVALUATION USING SUPER-RESOLUTION DEEP LEARNING RECONSTRUCTION TECHNIQUE: A MULTICENTER VALIDATION STUDY

Cheng Xu– PUMC

Conclusions: Compared with HIR, SR-DLR improves the visible and diagnostic performance of CCTA in stents evaluation.

Clinical Relevance/Application: SR-DLR algorithm improves the diagnostic accuracy and confidence of coronary stent evaluation.

Poster Discussion Sunday, November 30, 2025 at 12:15 PM CST

M5B-SPCA-5 | HIGH-RESOLUTION DEEP LEARNING CT RECONSTRUCTION FOR WATCHMAN DEVICE ASSESSMENT IN A CARDIAC PHANTOM

Martin Wagner, PhD – University of Wisconsin- Madison

Conclusions: PIQE reconstruction, particularly with a 1024 matrix size, offers significant advantages for visualizing and assessing a Watchman device in post-procedure CTs due to improved SNR, sharpness, and reduced metal artifacts.

Clinical Relevance/Application: Accurate post-procedural CT assessment of Watchman device placement is critical for detecting potentially life-threatening complications like migration, device-related thrombus, or peri-device leak. High-resolution deep learning reconstruction, such as PIQE1024, enhance visualization of fine device structures, thereby aiding in this crucial evaluation.

Poster Discussion Monday, December 1, 2025 at 12:45 PM CST

R5B-SPVA-3 | DEEP LEARNING ENHANCED ULTRA-LOW DOSE DUAL VASCULAR CTA: PROSPECTIVE VALIDATION OF 55% RADIATION & 21% CONTRAST REDUCTION WITH DIAGNOSTIC NON INFERIORITY

Lin Yang – Hanzhong Central Hospital

Conclusions: In comparison to the regular-dose protocol, the “dual-low” C&CC-CTA using DLR reconstruction demonstrates relatively better image quality while effectively reducing both radiation dose and contrast agent usage.

Clinical Relevance/Application: We propose a novel deep learning-enhanced "dual-low" coronary-carotid-cerebral CTA protocol, significantly reducing radiation by 55% and contrast by 21% while preserving diagnostic accuracy.

Poster Discussion Thursday, December 4, 2025 at 12:45 PM CST

T2-SPVA-1 | ENHANCED VISUALIZATION OF PORTAL VENOUS SYSTEM: CLINICAL VALUE OF CONTRAST ENHANCEMENT BOOST COMBINED WITH BLACK BLOOD TECHNIQUE IN CT ANGIOGRAPHY

Zhiman Lai– The First Affiliated Hospital of Sun Yat-sen University

Conclusions: The CE-Boost BB technique significantly enhances PV visualization by amplifying contrast, suppressing arterial interference, and improving SNR/CNR without protocol modifications. This innovation holds promise for refining diagnostic accuracy in PV-related pathologies while minimizing contrast-related risks.

Clinical Relevance/Application: The CE-Boost black blood technique enhances portal vein visualization by suppressing arterial interference and optimizing contrast, enabling precise preoperative planning for liver transplantation and management of portal hypertension while reducing contrast-related risks.

Poster Discussion Tuesday, December 2, 2025 at 9:00 AM CST

S3A-SPCA-8 | SYNERGISTIC IMPACT OF MULTIPLE DOSE REDUCTION STRATEGIES COMBINED WITH SUBTRACTION CORONARY CT ANGIOGRAPHY IN HIGH-CALCIFICATION PATIENTS

Mengqiang Xiao – Guangdong Provincial Hospital of Traditional Chinese Medicine Zhuhai Hospital

Conclusions: The integration of multiple dose reduction techniques with subtraction coronary CT angiography substantially lowers radiation exposure while enhancing the diagnostic accuracy for assessing coronary stenosis in patients with high calcification scores.

Clinical Relevance/Application: This advanced imaging protocol offers a promising noninvasive approach for patients with extensive coronary calcifications. By significantly reducing radiation dose without compromising image quality, the method enhances the reliability of coronary stenosis evaluation, thereby improving clinical decision-making and patient management in high-risk cardiovascular populations.

Poster Discussion Sunday, November 30, 2025 at 11:45 AM CST

R2-SPCA-10 | COMPARISON OF NON-GATED AND TRADITIONAL GATED TECHNIQUES IN AUTOMATED CORONARY ARTERY CALCIUM SCORING

Tao Zhou– Jinan People's Hospital

Conclusions: Non-gated coronary artery calcium (CAC) scoring using lung/mediastinum window parameters demonstrates significant correlation with traditional ECG-gated CAC scoring. However, the agreement between the two methods is stronger in low- to moderate-risk populations, suggesting that non-gated CAC scoring can serve as a preliminary screening tool for these groups.

Clinical Relevance/Application: The non-gated CAC scoring technique, when applied to low- to moderate-risk populations, helps avoid unnecessary additional ECG-gated CAC examinations, thereby reducing radiation exposure while maintaining diagnostic utility.

Poster Discussion Thursday, December 4, 2025 at 9:00 AM CST

T5A-SPCA-14 | ENHANCING ROBUSTNESS IN CORONARY ARTERY LUMEN AND ARTERIOSCLEROTIC PLAQUE FULL-AUTOMATED DETECTION: A DEEP LEARNING FRAMEWORK FOR CCTA ANALYSIS

Weifeng Guo– Zhongshan Hospital Affiliated to Fudan University

Conclusions: The proposed deep learning framework shows high accuracy and robustness in centerline extraction, lumen and plaque segmentation, and stenosis detection—even under challenging conditions in coronary artery pathologies and imaging quality. This enhances CCTA efficiency and consistency, leading to more reliable diagnostics.

Clinical Relevance/Application: This study provides a robust and high-precision CCTA analysis method, offering a powerful tool for clinical CCTA assessment to enhance the efficiency of clinical analysis and decision-making.

Poster Discussion Tuesday, December 2, 2025 at 12:15 PM CST

T5B-SPPH-3 | DEVELOPMENT OF A NEW PHANTOM FOR 3D IMAGING OF SMALL BLOOD VESSELS (WHICH ALLOWS SIMULTANEOUS MEASUREMENT OF MTF, SLICE THICKNESS, PEAK CT NUMBER, AND EFFECTIVE VOXEL SIZE)

Katsumi Tsujioka – Fujita Health University

Conclusions: The spiral wire phantom we developed allowed us to determine the MTF in the X-Y plane, the slice thickness in the Z-axis direction, and the peak CT value of the metal wire in a single scan. In addition, the effective voxel size could be determined from the increase in the measured CT value and the measured slice thickness. It was found that the effective voxel size was reduced in DLR and UHR CT compared to the conventional CT system.

Clinical Relevance/Application: The ability to visualize small blood vessels cannot be properly evaluated using only the spatial resolution based on the conventional MTF. This is because this method does not allow evaluation of the change in the peak CT value of small blood vessels due to the partial volume effect. The thickness of the metal wire in this phantom is 0.1 mm. This allows accurate evaluation of blood vessels with a diameter of 0.2 mm according to the sampling theorem. The new phantom, which allows evaluation of peak CT value and effective voxel size in addition to measurement of MTF and effective slice thickness in a single scan, is suitable for accurately comparing the accuracy of 3D image creation in clinical practice.

Poster Discussion Tuesday, December 2, 2025 at 12:45 PM CST

CAEE-86 | EFFECTIVENESS OF DEEP LEARNING-BASED IMAGE RECONSTRUCTION INCLUDING MOTION CORRECTION AND ITS POTENTIAL FOR RADIATION DOSE REDUCTION

Yamaguchi, MD – Hanaoka Seishu Memorial Hospital

Teaching Points:

1. Explaining the current status of factors that deteriorate coronary CT images and countermeasures.
2. Summarize of the relationship between heart rate during scan and motion artifacts, and the distribution of heart rate phases used for image reconstruction.
3. Overview of new coronary artery motion correction technology using deep learning.
4. The effectiveness of the motion correction technique at each heart rate will be verified using clinical cases by comparing it with conventional image reconstruction methods.
5. Proposal of an optimal scan protocol based on the relationship between image quality at each heart rates and selected cardiac phases.
6. The effectiveness of the proposed new imaging protocol in reducing radiation dose and improving image quality will be clarified through comparison with conventional imaging methods.

Educational Exhibit - On Demand

CAEE-11 | A NEW METHOD TO IMPROVE THE VISUALIZATION OF LATE IODINE ENHANCEMENT BY CT, EVEN AT HIGH HEART RATES

Takayoshi Yamaguchi – Hanaoka Seishu Memorial Hospital

Teaching Points:

1. Current status of acquisition and image reconstruction methods for myocardial late iodine enhancement (LIE) images using CT
2. Explain the advantages and limitations of low kV imaging compared to images with standard kV
3. Proposal of a new scanning method and image reconstruction method to improve contrast-to-noise ratio and reduce motion artifacts by utilizing the low radiation dose of low kV imaging
4. Validation of a new scanning method and image reconstruction method using a phantom simulating myocardial LIE imaging
5. Explains the effectiveness of the new method in clinical cases and how to use it appropriately, including the effect of reducing radiation dose

Educational Exhibit - On Demand

T1-SSPD03-6 | METAL ARTIFACT REDUCTION AND LOCAL RECURRENCE DETECTION IN PEDIATRIC AND ADOLESCENT PATIENTS WITH OSTEOSARCOMA LIMB SALVAGE SURGERY: VALUE OF COMBINATION OF SUBTRACTION CT AND SINGLE-ENERGY METAL ARTIFACT REDUCTION

Tianjing Chang - Beijing Shougang Hospital

Conclusions: The synergistic application of SCT and SEMAR effectively mitigates metallic artifacts, optimizes image quality, and enhances the detectability of local tumor recurrence with improved diagnostic confidence.

Clinical Relevance/Application: SCT-SEMAR can enhance the visualization and diagnostic confidence of local recurrence, providing critical imaging support for precision-guided therapeutic decision-making.

Scientific Session Tuesday, December 2, 2025 at 8:00 AM CST

R3-SSMK11-4 | HIGH DIAGNOSTIC ACCURACY OF CONTRAST-ENHANCED FIVE-PHASE ABDOMINAL CT FOR OPPORTUNISTIC BONE MINERAL DENSITY ASSESSMENT USING UNENHANCED CT AS REFERENCE STANDARD

Mengqiang Xiao - Guangdong Provincial Hospital of Traditional Chinese Medicine Zhuhai Hospital

Conclusions: Contrast-enhanced phases of five-phase abdominal CT demonstrate near-perfect agreement with unenhanced CT for opportunistic femoral bone density assessment. Any post-contrast phase can reliably opportunistically screen for osteoporosis without compromising diagnostic accuracy.

*Clinical Relevance/Application: Contrast-enhanced CT phases from routine abdominal scans can be reliably used for opportunistic osteoporosis screening, enabling bone mineral density assessment without the need for additional unenhanced imaging or radiation exposure.

Scientific Session Thursday, December 4, 2025 at 9:30 AM CST

W2-SPHN-8 | SUBTRACTION IODINE MAPS COMBINED WITH DEEP LEARNING RECONSTRUCTION IMPROVED EVALUATION OF TEMPORAL BONE LESIONS BASED ON ENHANCEMENT PATTERNS

Tong Su, MD -PUMC

Conclusions: The integration of SIM with DLR significantly improves temporal bone lesion assessment compared to conventional enhanced CT, particularly for hypervascular pathologies. This combined approach enhances noise reduction, anatomical delineation, and evaluation of bony involvement.

Clinical Relevance/Application: The SIM-DLR technique provides superior visualization of lesion invasion extent in the temporal bone, offering valuable preoperative information for surgical planning, especially in vascularized tumors.

Poster Discussion Wednesday, December 3, 2025 at 9:00 AM CST

T2-SPPH-8 | DUAL-PARAMETER OPTIMIZED ULTRA-LOW-DOSE CT FOR LUMBAR BONE MINERAL DENSITY ASSESSMENT: A PROSPECTIVE VALIDATION OF RADIATION REDUCTION AND DIAGNOSTIC ACCURACY

Mengqiang Xiao - Guangdong Provincial Hospital of Traditional Chinese Medicine Zhuhai Hospital

Conclusions: The dual-parameter optimized ULD-CT protocol substantially reduces radiation exposure while preserving sufficient image quality and high diagnostic accuracy for lumbar BMD assessment. This approach provides a safe and effective alternative for osteoporosis screening and longitudinal bone health monitoring in clinical practice.

Clinical Relevance/Application: The implementation of a dual-parameter ULD-CT protocol in routine clinical practice offers a significant advancement for early osteoporosis screening, particularly in high-risk populations. Its marked reduction in radiation dose allows for safe, repeated evaluations, enhancing patient management and follow-up care, especially in those with degenerative spine conditions or requiring frequent monitoring.

Poster Discussion Tuesday, December 2, 2025 at 9:00 AM CST

W5A-SPMK-2 | OPPORTUNISTIC OSTEOPOROSIS SCREENING IN HEPATOCELLULAR CARCINOMA PATIENTS USING THREE-PHASE CONTRAST-ENHANCED CT

Mengqiang Xiao - Guangdong Provincial Hospital of Traditional Chinese Medicine Zhuhai Hospital

Conclusions: Three-phase contrast-enhanced CT alone provides reliable femoral vBMD measurements and diagnostic accuracy—comparable to unenhanced QCT—in HCC patients, enabling combined tumor staging and opportunistic osteoporosis screening without additional imaging.

Clinical Relevance/Application: Opportunistic bone health assessment using routine three-phase CT in HCC patients facilitates early identification of osteoporosis in a high-risk population, leveraging existing scans to avoid extra radiation or protocol changes.

Poster Discussion Wednesday, December 3, 2025 at 12:15 PM CST

S3A-SPPH-5 | WHOLE-LUNG DYNAMIC PERFUSION AREA-DETECTOR CT IN NON-SMALL CELL LUNG CANCER WITH PROGRESSIVE FIBROSING INTERSTITIAL LUNG DISEASE

Yoshiharu Ohno, MD, PhD- Fujita Health University

Conclusions: Whole-lung dynamic CE-perfusion ADCT is useful for detecting pathological structural changes in stage I NSCLC patients with PF-ILD.

Clinical Relevance/Application: Whole-lung dynamic CE-perfusion ADCT is useful for detecting pathological structural changes in stage I NSCLC patients with PF-ILD.

Scientific Session Sunday, November 30, 2025 at 11:45 AM CST

R6-SSPH14-3 | A COMPARISON OF THE BIOMECHANICAL ASSESSMENT BETWEEN UPRIGHT AND SUPINE INSPIRATORY-EXPIRATORY AREA-DETECTOR CT IN PATIENTS WITH PROGRESSIVE PULMONARY FIBROSIS

Yoshiharu Ohno, MD, PhD - Fujita Health University

Conclusions: Upright ADCT has better potential than supine ADCT for detecting pulmonary functional loss and evaluating disease severity when paired inspiratory-expiratory ADCT is applied in PPF patients.

Clinical Relevance/Application: Upright ADCT has better potential than supine ADCT for pulmonary functional loss and disease severity evaluations when paired inspiratory-expiratory ADCT is performed in patients with progressive pulmonary fibrosis.

Scientific Session Thursday, December 4, 2025 at 1:30 PM CST

R6-SSPH14-6 | ARTIFICIAL INTELLIGENCE (AI-) BASED CAST SYSTEM FOR WHOLE-BODY CT: UTILITY FOR PULMONARY FUNCTIONAL LOSS AND LUNG ABNORMALITY CLASSIFICATION CAPABILITY AS COMPARED WITH AI-BASED CT TEXTURE ANALYSIS FOR CHEST CT IN JAPANESE HEALTH CHECKUP TEST COHORT

Yoshiharu Ohno, MD, PhD - Fujita Health University

Conclusions: AI-based CAST for whole-body CT has better potential than AI-based CT texture analysis for chest CT to assess pulmonary functional loss and discrimination of lung abnormalities in Japanese health checkup test cohort.

Clinical Relevance/Application: AI-based CAST has superior potential to CT texture analysis for pulmonary functional loss assessment and lung abnormality discrimination in Japanese health checkup test cohort.

Scientific Session Thursday, December 4, 2025 at 1:30 PM CST

M7-SSCH04-4 | DEEP LEARNING RECONSTRUCTION COMBINED WITH CONTRAST-ENHANCEMENT BOOST IN DUAL-LOW DOSE CT PULMONARY ANGIOGRAPHY: TWO-CENTER PROSPECTIVE TRIAL

Leilei Shen - Zhongshan Hospital Affiliated to Fudan University

Conclusions: DLR combined with CE-boost technique can significantly improve the image quality of CTPA with reduced radiation and contrast doses, facilitating a more accurate diagnosis of pulmonary embolism.

Clinical Relevance/Application: DLR-boost based low-radiation and low-contrast-dose CTPA protocol offers a novel strategy to further enhance the image quality and diagnosis accuracy for pulmonary embolism patients.

Scientific Session Monday, December 1, 2025 at 3:00 PM CST

M5A-SPCH-9 | INFLUENCE OF RADIATION DOSE REDUCTION AND RECONSTRUCTION ALGORITHMS TO QUANTITATIVE COPD EVALUATIONS ON HIGH-DEFINITION CT WITH SUPER-HIGH-RESOLUTION MODE IN SMOKERS

Yoshiyuki Ozawa, MD, PhD - Fujita Health University

Conclusions: HDCT with SHR mode has little influence of radiation dose reduction and reconstruction algorithm to quantitative CT evaluation of COPD in smokers.

*Clinical Relevance/Application: Quantitatively assessed HDCT with super-high-resolution mode has little influence of radiation dose reduction and reconstruction algorithm to quantitative CT evaluation of COPD in smokers.

Poster Discussion Monday, December 1, 2025 at 12:15 PM CST

M5A-SPCH-8 | DEEP LEARNING-GUIDED QUANTITATIVE TUMOR SIGNATURES EVALUATE IMMUNOTHERAPY RESPONSE: A MULTICENTER VALIDATION STUDY

Leilei Shen - Zhongshan Hospital Affiliated to Fudan University

Conclusions: The deep learning-guided semi-automatic segmentation approach enables rapid, reproducible tumor quantification and immunotherapy response assessment that closely matches expert radiologists. This tool holds promise for streamlining clinical workflows and reducing interobserver variability.

Clinical Relevance/Application: This semi-automatic segmentation software for quantitative analysis of advanced lung tumors post-immunotherapy serves as a valuable adjunct in clinical assessment. Automating tumor delineation reduces physicians’ workload and delivers objective efficacy metrics, supporting more personalized treatment decisions.

Poster Discussion Monday, December 1, 2025 at 12:15 PM CST

M2-SPCH-4 | DEVELOPMENT AND VALIDATION OF AUTOMATIC DETECTION MODEL OF ESOPHAGEAL FOREIGN BODIES BASED ON CT IMAGES: A MULTICENTER STUDY

Ouyang Zhiqiang, MD - Kunming Yan'an Hospital

Conclusions: Generally speaking, CT image analysis based on deep learning can significantly improve the diagnostic efficiency of esophageal foreign bodies, reduce the missed diagnosis rate (especially for tiny foreign bodies and transparent foreign bodies), and have the ability to dynamically predict the risk of complications.

Clinical Relevance/Application: Primary medical application: the model can replace inexperienced doctors to read films in resource-limited scenes, reducing the utilization rate of invasive examinations such as endoscopy. Optimization of emergency intervention: by predicting the risk of complications (such as perforation and aortic fistula), we can assist in formulating graded treatment plans and reduce the incidence of operation-related esophageal fistula.

Poster Discussion Monday, December 1, 2025 at 9:00 AM CST

M5A-SPCH-12 | PATHOLOGIC FIBROBLASTIC FOCI CORRELATE WITH CT-QUANTIFIED FIBROTIC PROGRESSION IN INTERSTITIAL LUNG DISEASE

Akira Haga, MD - Kanagawa Cardiovascuiar and Respiratory Center

Conclusions: QZIP-ILD progression rises in proportion to FF burden and, in upper lobes, to HNF4α expression, identifying both as quantitative markers of rapid ILD fibrosis progression.

Clinical Relevance/Application: Automated CT progression metrics combined with digitally quantified histology provide reproducible biomarkers for risk stratification, guide imaging follow-up, and can enrich patient selection and endpoints in future antifibrotic trials.

Poster Discussion Monday, December 1, 2025 at 12:15 PM CST

T5B-SPCH-7 | AUTOMATED 3D QUANTITATIVE ANALYSIS OF INTRAPULMONARY VASCULAR VOLUME IN VASCULITIS PATIENTS WITH PULMONARY VASCULAR INVOLVEMENT

Ying Ming - PUMC

Conclusions: The computer-aided pulmonary vascular segmentation algorithm can automatically measure IPVV, providing a quantitative evaluation of the condition of small pulmonary vessels affected by vasculitis.

Clinical Relevance/Application: The automated measurement of IPVV using a computer-aided pulmonary vascular segmentation algorithm enables objective and quantitative assessment of pulmonary vascular involvement in vasculitis patients.

Poster Discussion Tuesday, December 2, 2025 at 12:45 PM CST

T5A-SPCH-4 | DEEP LEARNING-BASED AUTOMATED SEGMENTATION OF PULMONARY VESSELS ON CHEST CT

Rui Zhao - PUMC

Conclusions: The nodule-aware and small vessel-optimized pulmonary vessel segmentation algorithm we designed can effectively avoid over-segmentation of pulmonary nodules and achieve superior vessel segmentation performance.

Clinical Relevance/Application: The deep learning segmentation algorithm for pulmonary vessels enables precise visualization of pulmonary arteries and veins on chest CT. Accurate segmentation of pulmonary vessels is crucial for both disease diagnosis and surgical planning.

Poster Discussion Tuesday, December 2, 2025 at 12:15 PM CST

R2-SPCH-4 | THE CHARACTERISTICS OF PULMONARY ARTERY INVOLVEMENT IN TAKAYASU ARTERITIS BASED ON CTPA

Ran Xiao - PUMC

Conclusions: TA-PAI is characterized by significant volume loss in intermediate-sized pulmonary arteries (1.6-3.2 mm), detectable via CTPA. PH-associated TA-PAI exhibits more severe structural changes (stenosis, dilation, aneurysms), but PAV alone did not differentiate PH status, possibly due to sample size limitations.

Clinical Relevance/Application: Quantitative CTPA analysis of PAV, particularly in 1.6-3.2 mm arteries, may aid early TA-PAI diagnosis and monitoring. The association of PH with arterial dilation/aneurysms underscores the need for vigilant hemodynamic assessment in TA-PAI. Further studies should validate PAV thresholds for disease stratification and explore longitudinal changes.

Poster Discussion Thursday, December 4, 2025 at 9:00 AM CST

T5A-SPCH-2 | EVALUATION OF IMPAIRED LUNG DEFORMATION DURING EXPIRATION IN COPD USING FOUR-DIMENSIONAL DYNAMIC-VENTILATION CT

Yanyan Xu, MD, PhD - China-Japan Friendship Hospital

Conclusions: Decreased lung deformation during expiration was associated with loss of lung function. Strain-related parameters, especially those derived from the whole expiration phase, showed promising potential in indicating the severity of airflow limitation in patients with COPD.

Clinical Relevance/Application: This study demonstrates that reduced lung deformation during expiration, measured by 4D dynamic-ventilation CT strain analysis, correlates with worsening airflow limitation in COPD, offering a novel imaging biomarker for disease severity assessment. The findings highlight the clinical potential of whole-expiration-phase strain parameters in evaluating functional impairment and optimizing COPD management strategies.

Poster Discussion Tuesday, December 2, 2025 at 12:15 PM CST

CHEE-88 | RADIOLOGICAL-PATHOLOGICAL CORRELATION IN CONNECTIVE TISSUE DISEASE-ASSOCIATED LUNG DISEASES

Tae Iwasawa, MD, PhD

Teaching Points: Computed tomography (CT) findings in connective tissue disease-associated interstitial lung disease (CTD-ILD) are often complex due to overlapping pathological features such as bronchiolitis, usual interstitial pneumonia (UIP), and nonspecific interstitial pneumonia (NSIP). As ILD classification is primarily histopathological, radiologists must understand the pathological correlates of these imaging patterns. However, according to the 2023 ILD guidelines of the American College of Rheumatology, surgical lung biopsy is not recommended for suspected CTD unless malignancy is suspected. This study describes CT images with corresponding histological findings in patients not initially diagnosed with CTD to help radiologists understand CTD-associated lung disease.

Educational Exhibit – ON DEMAND

CHEE-93 | CHEST CT USING SILVER BEAM FILTER: LUNG NODULE DETECTION WITH ULTRA-LOW RADIATION DOSE

Hiroshi Moriya, MD, PhD - Ohara General Hospital

Teaching Points:

1. Reduction of radiation exposure with Silver Beam Filter
2. Image quality evaluation of CT equipped with Silver Beam Filter: Phantom-based evaluation
3. Pulmonary nodule detection capability of ultra-low-dose CT equipped with Silver Beam Filter

Educational Exhibit – ON DEMAND

CHEE-85 | BEYOND INVASIVE ADENOCARCINOMA: A VISUAL GUIDE TO PERSISTENT SUBSOLID PULMONARY NODULES ON CT

Yanyan Xu, MD, PhD, - China-Japan Friendship Hospital

Teaching Points:

1. Classify the spectrum of persistent SSNs into neoplastic (adenocarcinoma spectrum) and non-neoplastic (infectious/inflammatory) etiologies.
2. Identify key CT features to differentiate benign vs. malignant SSNs
3. Propose evidence-based management pathways based on Fleischner Society guidelines

Educational Exhibit – ON DEMAND